Product description

Antisedan is prescribed for dogs for the reversal of the sedative and analgesic effects of Dexdomitor and Dexdomitor 0.1. Antisedan contains 5 mg/ml of atipamezole hydrochloride, which acts as a dexmedetomidine reversing agent. Dexmedetomidine is the active ingredient in Dexdomitor that has a sedative and analgesic effect. Antisedan safely and reliably reverses the effects of Dexdomitor and Dexdomitor 0.1, 5-10 minutes after the injection. It is administered intramuscularly for use only in dogs. Antisedan reduces the sedation time, which allows your dog to return home awake and ambulatory, avoiding a full day or an overnight stay at the clinic. Antisedan Injectable Solution for dogs is available in a 10 ml vial.

Active ingredients

Each mL of Antisedan contains 5.0 mg atipamezole hydrochloride, 1.0 mg methylparaben, 8.5 mg sodium chloride, and water for injection

Indications for use

Antisedan is indicated for the reversal of the sedative and analgesic effects of Dexdomitor (dexmedetomidine hydrochloride), and Domitor (medetomidine hydrochloride) in dogs.

Administration and dosage

Antisedan is administered intramuscularly (IM) for reversal of sedation and analgesia regardless of the route used for Dexdomitor or Domitor. The atipamezole dose for the reversal of IV Dexdomitor or Domitor is 3750 mcg/m2. The atipamezole dose for the reversal of IM Dexdomitor or Domitor is 5000 mcg/m2.

The dosage of Antisedan is calculated based on body surface area. Use the tables in the pdf in the prescribing information section below to determine the correct injection volume or the correct Antisedan dosage on the basis of kilograms of body weight.

Note that the mcg/kg dosage decreases as body weight increases.

Prescribing information