Product description

Simplicef is an antimicrobial for oral use in dogs.

Active ingredients

Each tablet of Simplicef contains:

Indications for use

Simplicef is indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of Staphylococcus pseudintermedius, Staphylococcus aureus, Streptococcus canis (group G, ß hemolytic), Escherichia coli, Pasteurella multocida, and Proteus mirabilis.

Administration and dosage

• The dose range of Simplicef is 5-10 mg/kg (2.3-4.5 mg/lb) body weight, administered orally, once a day. The dose may be given with or without food.

• The determination of dosage for any particular patient must take into consideration such factors as the severity and nature of the infection, the susceptibility of the causative organisms, and the integrity of the patient’s host-defense mechanisms.

• Obtain a sample of the pathogenic organism for culture and sensitivity testing prior to beginning antimicrobial therapy. Once results become available, continue with appropriate therapy.

• Simplicef tablets should be administered once daily for 5-7 days or for 2-3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Treatment of acute infections should not be continued for more than 3-4 days if no response to therapy is seen.

• Dose Table for Simplicef Tablets at 5 mg/kg Total Daily Dosage:

• Dose Table for Simplicef Tablets at 10 mg/kg Total Daily Dosage:

Prescribing information