Factrel Injection
For the treatment of ovarian follicular cysts
Factrel Injection
For the treatment of ovarian follicular cysts
Product description
Factrel Injection is an solution for intramuscular injection in cattle.
Active ingredients
Each mL of Factrel Injection contains:
- Synthetic gonadorelin (as hydrochloride) 50 micrograms in aqueous formulation containing 0.6% sodium chloride and 2% benzyl alcohol (as a preservative).
Indications for use
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Factrel Injection is indicated for the treatment of ovarian follicular cysts in lactating dairy cows, beef cows, and replacement dairy and beef heifers.
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The treatment effect of Factrel Injection when used in lactating dairy cows, beef cows, and replacement dairy and beef heifers is a reduction in the number of days to first estrus.
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For use with Lutalyse (dinoprost tromethamine injection) Injection to synchronize estrous cycles to allow fixed-time artificial insemination (FTAI) in lactating dairy cows.
Administration and dosage
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For the treatment of ovarian follicular cysts in lactating dairy cows, beef cows, and replacement dairy and beef heifers:
- Administer 2 mL of Factrel Injection as a single intramuscular injection.
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For use with Lutalyse (dinoprost tromethamine injection) Injection to synchronize estrous cycles to allow fixed-time artificial insemination (FTAI) in lactating dairy cows:
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Administer 2 to 4 mL Factrel Injection (100-200 mcg gonadorelin) per cow as an intramuscular injection in a treatment regimen with the following framework:
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Administer the first dose of Factrel Injection (2-4 mL) at Day 0
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Administer Lutalyse (25 mg dinoprost, as dinoprost tromethamine injection) Injection by intramuscular injection 6-8 days after the first dose of Factrel Injection.
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Administer a second dose of Factrel Injection (2-4 mL) 30 to 72 hours after the Lutalyse injection.
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Perform FTAI 0 to 24 hours after the second dose of Factrel Injection, or inseminate cows on detected estrus using standard herd practices.
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Below are three examples of treatment regimens for FTAI that fit within the dosage regimen framework described immediately above:
Example 1 | Example 2 | Example 3 | |
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Day 0 (Monday) | 1st FACTREL | 1st FACTREL | 1st FACTREL |
Day 7 (the following Monday | )LUTALYSE | LUTALYSE | LUTALYSE |
Day 9(Wednesday) | 2nd FACTREL + FTAI at 48 hours after LUTALYSE | 2nd FACTREL 48 hours after LUTALYSE | 2nd FACTREL 56 hours after LUTALYSE |
Day 10 (Thursday) | FTAI 24 hours after 2nd FACTREL | FTAI 18 hours after 2nd FACTREL |