Product description

Allopurinol tablets reduces serum and urinary uric acid concentrations.

Active ingredients

Each Allopurinol tablet contains:

Indications for use

Allopurinol is indicated in:

• The management of patients with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy).

• The management of patients with leukemia, lymphoma and malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels. Treatment with allopurinol tablets USP should be discontinued when the potential for overproduction of uric acid is no longer present.

• The management of patients with recurrent calcium oxalate calculi whose daily uric acid excretion exceeds 800 mg/day in male pets and 750 mg/day in female pets. Therapy in such patients should be carefully assessed initially and reassessed periodically to determine in each case that treatment is beneficial and that the benefits outweigh the risks.

Administration and dosage

• The dosage varies with the severity of the disease. The average is 200 to 300 mg per day for pets with mild gout and 400 to 600 mg per day for those with moderately severe tophaceous gout. The appropriate dosage may be administered in divided doses or as a single equivalent dose with the 300 mg tablet. Dosage requirements in excess of 300 mg should be administered in divided doses. The minimal effective dosage is 100 to 200 mg daily and the maximal recommended dosage is 800 mg daily. To reduce the possibility of flare-up of acute gout attacks, it is recommended that the pet start with a low dose of allopurinol (100 mg daily) and increase at weekly intervals by 100 mg until a serum uric acid level of 6 mg/dL or less is attained but without exceeding the maximal recommended dosage.

• Use as directed by your veterinarian

Prescribing information